SR 3677

Catalogue number: S684100
Chemical name: SR 3677
Synonyms: N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide;
CAS Number: 1072959-67-1
Possible CAS #: NA
Molecular form.: C₂₂H₂₄N₄O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 408.45
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: SR 3677 is an ATP-competitive inhibitor of Rho-kinases (ROCK-I/ROCK-II) which reduces amyloid-β production. It’s hypothesized that Alzheimer’s Disease, can be treated with this type of treatment, and delay further progression of the disease.
Dangerous Goods Info: NA
References: Herskowitz, J. et al.: J. Neurosci., 33, 19086 (2013); Feng, Y. et al.: J. Med. Chem., 51, 6642 (2008);
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $110.00
100mg $1125.00
  Pack size Price(USD)
25mg $375.00
Exact Weight Packaging ($75(USD) / Vial)
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