D-erythro-Sphingosine-1-phosphate

Catalogue number: S681500
Chemical name: D-erythro-Sphingosine-1-phosphate
Synonyms: (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-(Dihydrogen phosphate); Sphingosine-1-phosphate; SPN-1-P; S1P.
CAS Number: 26993-30-6
Possible CAS #: NA
Molecular form.: C₁₈H₃₈NO₅P
Appearance: Off-White to Pale Beige Solid
Melting Point: 150-154ºC
Mol. Weight: 379.47
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Acetic Acid (Slightly, Heated)
Stability: Moisture, Temperature Sensitive; Hygroscopic
Category: Activators, Glycerols, Fatty Acid Derivatives & Lipids, Inhibitors, Protein Kinase Inhibitors and Activators
Boiling Point: No Data Available
Applications: A putative lipid second messenger; found to inhibit cellular mobility of melanoma cells at very low concentrations with no toxic effects thereby making it a possible agent for prevention of tumor cell metastasis and inflammatory processes; mobilizes intracellular calcium stores; decreases cellular cAMP; activates phospholipase D; does not inhibitprotein kinase C.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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