Sofosbuvir 5’-Desphosphate 3’-O-[(S)-Phosphate]

Catalogue number: S675610
Chemical name: Sofosbuvir 5’-Desphosphate 3’-O-[(S)-Phosphate]
Synonyms: (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate
CAS Number: 1337482-15-1
Possible CAS #: NA
Molecular form.: C₂₂H₂₉FN₃O₉P
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 529.45
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Heterocycles, Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Sofosbuvir 5’-Desphosphate 3’-O-[(S)-Phosphate] is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-α-fluoro-β-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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