Sofosbuvir Carboxylic Acid

Catalogue number: S675600
Chemical name: Sofosbuvir Carboxylic Acid
Synonyms: (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoic Acid
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₁₉H₂₃FN₃O₉P
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 487.37
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Phosphorylating and Phosphitylating Agents
Boiling Point: No Data Available
Applications: Sofosbuvir Carboxylic Acid is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-α-fluoro-β-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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