SN-38 Carboxylate Disodium Salt

Catalogue number: S589960
Chemical name: SN-38 Carboxylate Disodium Salt
Synonyms: (αS)-α,12-Diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-9-indolizino[1,2-b]quinoline-7-acetic Acid Disodium Salt; SN 38 Acid Sodium Salt;
CAS Number: NA
Possible CAS #: 142677-15-4-carboxylic acid
Molecular form.: C₂₂H₂₀N₂Na₂O₆
Appearance: Yellow Solid
Melting Point: >220°C (dec.)
Mol. Weight: 454.38
Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility: DMSO, Methanol, Water
Stability: No Data Available
Category: Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: The active metabolite of Irinotecan (carboxylate form). SN-38 lactone and carboxylate may be considered pharmacokinetically distinct agents.
Dangerous Goods Info: NA
References: Billecke, S., et al.: Drug Metab. Dispos., 28, 1335 (2000), Teiber, J., et al.: Biochem. Pharmacol., 66, 887 (2003), Ashley, G., et al.: J. Antibiot., 57, 224 (2004),
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $140.00
5mg $575.00
  Pack size Price(USD)
2.5mg $310.00
10mg $1120.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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