Catalogue number: S564750
Chemical name: SMER3
Synonyms: 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one; 9H-Indeno[1,2-b][1,2,5]oxadiazolo[3,4-e]pyrazin-9-one; 2-Oxa-1,3,4,10-tetraazacyclopenta[b]fluoren-9-one
CAS Number: 67200-34-4
Possible CAS #: NA
Molecular form.: C₁₁H₄N₄O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 224.18
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Pharmaceuticals, Intermediates & Fine Chemicals, Amines, Aromatic, Heterocycle, Inhibitor
Boiling Point: No Data Available
Applications: SMER3 is used in biological studies to evaluate the pharmacological activity as it is discovered as an inhibitor. SMER3 inhibits mTOR (mammalian target of rapamycin) which plays a key role in the growth control in eukaryotic cells. SMER is the small-molecule enhancer of rapamycin.
Dangerous Goods Info: NA
References: Aghajan, M., et al.: Nat. Biotechnol., 28, 738 (2010)
Peer Review Product Citations: Aghajan, M., et al.: Nat. Biotechnol., 28, 738 (2010)

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