SMAD3 Inhibtor, SIS 3-d3

Catalogue number: S564502
Chemical name: SMAD3 Inhibtor, SIS 3-d3
Synonyms: 1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-d3-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one
CAS Number: 1512629-88-7
Possible CAS #: NA
Molecular form.: C₂₈H₂₄D₃N₃O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 456.55
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: SMAD3 Inhibtor, SIS 3-d3 is the labeled analogue of SMAD3 Inhibtor, SIS 3 (S564500), which selectively inhibits TGF-β and activin. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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