SMAD3 Inhibtor, SIS 3

Catalogue number: S564500
Chemical name: SMAD3 Inhibtor, SIS 3
Synonyms: 1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one
CAS Number: 1009104-85-1
Possible CAS #: NA
Molecular form.: C₂₈H₂₇N₃O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 453.53
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: SMAD3 Inhibitor, SIS3 selectively inhibits TGF-β and activin. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.
Dangerous Goods Info: NA
References: Jinnin, M., et al.: Mol. Pharmacol., 69, 597 (2006)
Peer Review Product Citations:

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  Pack size Price(USD)
2.5mg $125.00
25mg $780.00
  Pack size Price(USD)
5mg $195.00
Exact Weight Packaging ($75(USD) / Vial)
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