Silybin A

Catalogue number: S465855
Chemical name: Silybin A
Synonyms: (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one; 3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxan-6-yl]-4-chromanone; [2R-[2α,3β,6(2R*,3R*)]]-2-[2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one; Silybin; 1,4-Benzodioxin, 4H-1-benzopyran-4-one deriv.; 7C3MT; Mepasil; Silibinin; Silibinin A; Silliver; Silybin b1; Silybine; Silybum substance E6; Silymarin I; Silymarin MZ 80; Silymarine I
CAS Number: 22888-70-6
Possible CAS #: Silybin B: 142797-34-0 / Diastereomer Mixture: 802
Molecular form.: C₂₅H₂₂O₁₀
Appearance: Pale Yellow Solid
Melting Point: 173-176°C
Mol. Weight: 482.44
Storage: No Data Available
Solubility: Acetone (Sparingly), DMSO, Methano (Sparingly)
Stability: No Data Available
Category: Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Silybin A is the 2R, 3R, 7‘R, 8‘R isomer of Silybin (S465850); a natural occurring flavolignan that exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells.
References: Lee, D.Y.W, et al.: J. Nat. Prod., 66, 1171 (2003); Trappoliere, M., et al.: J. Hepatol., 50, 1102 (2009); Borsari, M., et al.: J. Inorg. Biochem., 85, 123 (2001)
Dangerous Goods Info: NA

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