Semagacestat

Catalogue number: S255600
Chemical name: Semagacestat
Synonyms: (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide; LY 450139;
CAS Number: 425386-60-3
Possible CAS #: NA
Molecular form.: C₁₉H₂₇N₃O₄
Appearance: White Solid
Melting Point: 213-215°C
Mol. Weight: 361.44
Storage: -20˚C Freezer
Solubility: DMSO (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (Aβ), a neurotoxic endogenous peptide believed to be involved in the pathogenesis of Alzheimer’s disease (AD).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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