Catalogue number: S253500
Chemical name: Selisistat
Synonyms: 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide; 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic Acid Amide; EX 527
CAS Number: 49843-98-3
Possible CAS #: NA
Molecular form.: C₁₃H₁₃ClN₂O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 248.71
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Selisistat is a potent and selective sirtuin 1 (SIRT1) inhibitor identified from a high throughput screen. It is more selective (200-500-fold) for SIRT1 than for SIRT2 or SIRT3 and has been shown to be a potent SIRT6 inhibitor using H3K56 deacetylation site based substrate.
References: Kokkonen, P., et al.: Eur. J. Pharm. Sci., 63, 71 (2014); Zhang, Y., et al.: Oncogene, 28, 445 (2009)
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package

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