SB 202190

Catalogue number: S154495
Chemical name: SB 202190
Synonyms: 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol
CAS Number: 152121-30-7
Possible CAS #: NA
Molecular form.: C₂₀H₁₄FN₃O
Appearance: Light Yellow Solid
Melting Point: >178°C (dec.)
Mol. Weight: 331.34
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase and Activators,
Boiling Point: No Data Available
Applications: SB 202190 is a DFG inhibitor used in the treatment of colorectal cancer. It is a highly selective, potent inhibitor of p38 MAP kinase. SB-202190 is able to promote proliferation of C6 cells in lower concentration but induced apoptosis in higher levels. Studies show that SB202190 can protect neural function from ischemia/reperfusion injury and regulate the activation of Bcl-2 and Bax protein after ischemia/reperfusion in rat.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $110.00
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25mg $325.00
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  Pack size Price(USD)
10mg $150.00
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100mg $1075.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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