Saxagliptin Cyclic Amide

Catalogue number: S143530
Chemical name: Saxagliptin Cyclic Amide
Synonyms: (1aS,4S,6aR,7aS)-Hexahydro-4-(3-hydroxytricyclo[,7]dec-1-yl)-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-3,6-dione
CAS Number: 1350800-77-9
Possible CAS #: NA
Molecular form.: C₁₈H₂₄N₂O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 316.39
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Saxagliptin Cyclic Amide is a degradation product of Saxagliptin (S143500); a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.
Dangerous Goods Info: NA
References: Jones, G.S., et al.: J. Org. Chem., 76, 10332 (2011); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008)
Peer Review Product Citations:

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