Ruboxistaurin-d6 Hydrochloride

Catalogue number: R701527
Chemical name: Ruboxistaurin-d6 Hydrochloride
Synonyms: (9S)-9-[[(Dimethyl-d6)amino]methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-Dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione Hydrochloride; LY 333531-d6;
CAS Number: 1794767-04-6
Possible CAS #: unlabelled: 169939-93-9
Molecular form.: C₂₈H₂₃D₆ClN₄O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 511.04
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Labelled Ruboxistaurin. Ruboxistaurin is a protein kinase C (PKC) β inhibitor, exhibits significant anti-angiogenic activity that reduces the response of vascular endothelial cells to stimulation by vascular endothelial growth factor (VEGF). Ruboxistaurin is used in treatment of diabetic microvascular complications.
Dangerous Goods Info: NA
References: Miller, J. et al.: Diabetes Metab. Rev., 13, 37 (1997); Suzuma, I. et al.: J. Biol. Chem., 277, 1047 (2002),;Ali, N. et al.: J. Pharmacol. Sci., 98, 130 (2005);
Peer Review Product Citations:

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