RN 486

Catalogue number: R637000
Chemical name: RN 486
Synonyms: 6-Cyclopropyl-2-[3-[1,6-dihydro-1-methyl-5-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-6-oxo-3-pyridinyl]-2-(hydroxymethyl)phenyl]-8-fluoro-1(2H)-Isoquinolinone;
CAS Number: 1242156-23-5
Possible CAS #: NA
Molecular form.: C₃₅H₃₅FN₆O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 606.69
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: RN 486 is a Bruton’s tyrosine kinase (Btk) inhibitor, blocking receptor cross-linking-induced degranulation in mast cells. May be used in the prevention of arthritis and other autoimmune diseases.
Dangerous Goods Info: NA
References: Xu, D. et al.: J. Pharmacol. Exp. Ther., 34, 90 (2012);
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $90.00
25mg $575.00
  Pack size Price(USD)
5mg $175.00
50mg $875.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Available in 2-3 weeks

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