Catalogue number: R279002
Chemical name: Retrorsine-D4
Synonyms: (3Z,5R,6S,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione-D4; 12,18-Dihydroxy-senecionan-11,16-dione-D4; NSC 107659-D4; Retrorsin-D4; [5R-(3Z,5R*,6S*,14aR*,14bR*)]-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione-D4; β-Longilobine-D4
CAS Number: NA
Possible CAS #: Unlabelled: 480-54-6
Molecular form.: C₁₈H₂₁D₄NO₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 355.42
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Retrorsine-D4 is a labelled analogue of Retrorsine (R279000). Retrorsine is a pyrrolizidine alkaloid that blocks the hepatocyte cell cycle, ultimately affecting hepatocyte proliferative capacity.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References: Gordon, G., et al.: Hepatology, 32, 312 (2000); Laconi, E., et al.: Am. J. Path., 153, 319 (1998)
Peer Review Product Citations:

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