Regorafenib N-β-D-Glucuronide (Pyridine)-N-oxide

Catalogue number: R143325
Chemical name: Regorafenib N-β-D-Glucuronide (Pyridine)-N-oxide
Synonyms: 4-(4-(3-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)-3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-(methylcarbamoyl)pyridine 1-Oxide
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₇H₂₃ClF₄N₄O₁₀
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 674.94
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Glucuronides, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Regorafenib N-β-D-Glucuronide (Pyridine)-N-oxide is a derivative of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent.
Dangerous Goods Info: NA
References: Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)
Peer Review Product Citations:

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