Catalogue number: R143002
Chemical name: Regorafenib-d3
Synonyms: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-(methyl-d3)-2-pyridinecarboxamide
CAS Number: 1255386-16-3
Possible CAS #: Unlabelled: 755037-03-7
Molecular form.: C₂₁H₁₂D₃ClF₄N₄O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 485.83
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Regorafenib-d3 is the isotope labelled analog of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM and is useful for the treatment of inflammation. Also an anti-proliferative agent.
Dangerous Goods Info: NA
References: Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)
Peer Review Product Citations:

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