Regorafenib

Catalogue number: R143000
Chemical name: Regorafenib
Synonyms: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N’-(4-Chloro-3-trifluoromethylphenyl)ureido]-3- fluorophenoxy]pyridine-2-carboxylic Acid Methylamide;
CAS Number: 755037-03-7
Possible CAS #: NA
Molecular form.: C₂₁H₁₅ClF₄N₄O₃
Appearance: Light Pink Solid
Melting Point: 204-206°C
Mol. Weight: 482.82
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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