28-O-Methyl-rapamycin

Catalogue number: R124020
Chemical name: 28-O-Methyl-rapamycin
Synonyms: 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine Rapamycin Deriv.;
CAS Number: 159351-88-9
Possible CAS #: NA
Molecular form.: C₅₂H₈₁NO₁₃
Appearance: White Solid
Melting Point: >102°C (dec.)
Mol. Weight: 928.2
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 28-O-Methyl-rapamycin is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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