Catalogue number: R124020
Chemical name: 28-O-Methyl-rapamycin
Synonyms: 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine Rapamycin Deriv.;
CAS Number: 159351-88-9
Possible CAS #: NA
Molecular form.: C₅₂H₈₁NO₁₃
Appearance: White Solid
Melting Point: >102°C (dec.)
Mol. Weight: 928.2
Storage: No Data Available
Solubility: Ethyl Acetate (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 28-O-Methyl-rapamycin is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
Dangerous Goods Info: NA
References: Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
1mg $150.00
  Pack size Price(USD)
10mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Production

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »