R406

Catalogue number: R060000
Chemical name: R406
Synonyms: 6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one Monobenzenesulfonate;
CAS Number: 841290-81-1
Possible CAS #: NA
Molecular form.: C₂₂H₂₃FN₆O₅•C₆H₆O₃S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 538.55
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: R406 is a potent Syk inhibitor which affects Dectin-1-mediated signalling in mammilian cells. R406 thus acts an anti-fungal agent. Also a potential anti-leukemia agent, through modulation of sphingosine-1 phosphate receptor 1 (S1PR1).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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