Pyridone 6

Catalogue number: P991730
Chemical name: Pyridone 6
Synonyms: 2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5-f]isoquinolin-7-one;CMP 6;
CAS Number: 457081-03-7
Possible CAS #: NA
Molecular form.: C₁₈H₁₆FN₃O
Appearance: Brown Solid
Melting Point: >240°C (dec.)
Mol. Weight: 309.34
Storage: -20˚C Freezer
Solubility: DMSO
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Pyridone 6 is a ATP-competitive JAK inhibitor in clinical development for the treatment of myeloproliferative neoplasms and B cell acute lymphoblastic leukemia.
Dangerous Goods Info: NA
References: Hornakova, T., et al.: Haematologica., 96, 845 (2011); Weigert, O., et al.: J. Exp. Med., 209, 259 (2012); Nakagawa, R., et al.: J. Immunol., 187, 4611 (2011);
Peer Review Product Citations:

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  Pack size Price(USD)
.5mg $65.00
5mg $285.00
25mg $995.00
  Pack size Price(USD)
1mg $110.00
10mg $470.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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