Catalogue number: P841520
Chemical name: N-(2-Pyrazinylcarbonyl)-L-phenylalanyl-N-[(1R)-1-borono-3-hydroxy-3-methylbutyl]-L-phenylalaninamide
Synonyms: ((R)-3-Hydroxy-3-methyl-1-((S)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic Acid
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₈H₃₄BN₅O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 547.41
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Boron Derivatives, Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: N-(2-Pyrazinylcarbonyl)-L-phenylalanyl-N-[(1R)-1-borono-3-hydroxy-3-methylbutyl]-L-phenylalaninamide is an impurity of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
Dangerous Goods Info: NA
References: Nawrocki, S.T., et al.: Cancer Res., 65, 11510 (2005); Drahl, C.: Chem. and Eng. News, 87, 41 (2009)
Peer Review Product Citations:

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