PU-H71 Trifluoroacetic Acid

Catalogue number: P840115
Chemical name: PU-H71 Trifluoroacetic Acid
Synonyms: 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Trifluoroacetic Acid;
CAS Number: 873436-91-0
Possible CAS #: Free Base: 873436-91-0
Molecular form.: C₂₀H₂₁F₃IN₆O₃S
Appearance: Off-White to Pale Beige Solid
Melting Point: >194ºC (dec.)
Mol. Weight: 609.38
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: Trifluoroacetic Acid of PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease.
Dangerous Goods Info: NA
References: Gewirth, D.T., et al.: J. Med. Chem., 49, 381 (2006), Taldone, T., et al.: Bioorh. Med. Chem., 17, 2225 (2009),
Peer Review Product Citations:

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  Pack size Price(USD)
10mg $150.00
  Pack size Price(USD)
100mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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