Propyl Methanethiosulfonate

Catalogue number: P838250
Chemical name: Propyl Methanethiosulfonate
Synonyms: PMTS; Methanesulfonothioic Acid S-Propyl Ester;
CAS Number: 24387-69-7
Possible CAS #: NA
Molecular form.: C₄H₁₀O₂S₂
Appearance: Clear Colourless Oil
Melting Point: N/A
Mol. Weight: 154.25
Storage: Refrigerator
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: MTS & Sulfhydryl Active Reagents
Boiling Point: 85°C/0.5 mm
Applications: Reacts specifically and rapidly with thiols to form mixed disulfides. PMTS covalently binds to cystein residues introduced into a specific second transmembrane site in the glycine receptor and g-aminobutyric acid type A receptor subunits and irreversibly enhances receptor function.
Dangerous Goods Info: NA
References: Xu, M. & Akabus, M.H.: J. Biol. Chem., 268, 21505 (1993), Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Mascia, M.P., et al.: P. Natl. Acad. Sci., 97, 16, 9305 (2000)
Peer Review Product Citations:

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