Catalogue number: P700500
Chemical name: Pralatrexate
Synonyms: N-[4-[1-[(2,4-Diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-L-glutamic Acid; N-[4-[1-[(2,4-Diamino-6-pteridinyl)methyl]-3-butynyl]benzoyl]-L-glutamic Acid; 10-Propargyl-10-deazaaminopterin; Folotyn; PDX;
CAS Number: 146464-95-1
Possible CAS #: NA
Molecular form.: C₂₃H₂₃N₇O₅
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 477.47
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amino Acids & Derivatives, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: An antifolate with high affinity for the reduced folate carrier-type 1, produces marked complete and durable remissions in a diversity of chemotherapy refractory cases of T-cell lymphoma.
Dangerous Goods Info: NA
References: Krug, L.M. et al.: Clin. Cancer Res., 6, 3493 (2000); O’Connor, O.A. et al.: Br. J. Haematol., 139, 425 (2007); O’Connor, O.A. et al.: J. Clin. Oncol., 29, 1182 (2011);
Peer Review Product Citations:

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