Pixantrone-N7-desethanamine Dihydrochloride

Catalogue number: P552505
Chemical name: Pixantrone-N7-desethanamine Dihydrochloride
Synonyms: N7-(Desaminoethyl)-Pixantrone Dihydrochloride; 6-Amino-9-[(2-aminoethyl)amino]-benz[g]isoquinoline-5,10-dione Dihydrochloride
CAS Number: NA
Possible CAS #: free base: 1430561-04-8
Molecular form.: C₁₅H₁₄N₄O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 282.3
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Pixantrone-N7-desethanamine Dihydrochloride is an impurity of Pixantrone (P552500), an antineoplastic drug belonging to group of antitumor antibiotics. Pixantrone is an anlogue of Mitoxantrone (M373425) and is just as potent in the treatment of multiple sclerosis with fewer toxic effects on cardiac tissue. Studies suggest that Pixantrone significantly reduces amyloid beta (A beta(1-42)) neurotoxicity, a mechanism implicated in Alzheimer’s disease.
Dangerous Goods Info: NA
References: Cavalletti, E. et al.: Invest. New Drugs, 25, 187 (2007); Gonsette, R.E. et al.: J. Neurol. Sci., 223, 81 (2004); Colombo, R. et al.: Electrophoresis, 30, 1418 (2009)
Peer Review Product Citations:

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5mg $740.00
  Pack size Price(USD)
2.5mg $390.00
10mg $1400.00
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