Catalogue number: P458532
Chemical name: (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methylbutane-1-boronate-d8
Synonyms: N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide;
CAS Number: NA
Possible CAS #: 205393-22-2-unlabelled
Molecular form.: C₂₉H₃₁D₈BN₄O₄
Appearance: Yellow Solid
Melting Point: No Data Available
Mol. Weight: 526.5
Storage: No Data Available
Solubility: Chloroform, Dimethyl Sulfoxide, Ethanol, Ethyl Acetate,
Stability: No Data Available
Category: Boron Derivatives, Chiral Reagents, Intermediates, Isotope Labelled Compounds
Boiling Point: No Data Available
Applications: Intermediate in the preparation of Bortezomib (B675700), a dipeptidyl boronate proteasome inhibitor.
References: Zhu, Y., et al.: Bioorg. Med. Chem., 14, 1483 (2006), Dorsey, B., et al.: J. Med. Chem., 51, 1068 (2008), Zhu, Y., et al.: Eur. J .Med. Chem., 44, 1486 (2009),
Dangerous Goods Info: NA

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