2-(Phosphonomethyl)pentanedioic Acid

Catalogue number: P353900
Chemical name: 2-(Phosphonomethyl)pentanedioic Acid
Synonyms: PMPA (NAALADase inhibitor); 2-(Phosphonomethyl)pentane-1,5-dioic Acid
CAS Number: 173039-10-6
Possible CAS #: NA
Molecular form.: C₆H₁₁O₇P
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 226.12
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 2-(Phosphonomethyl)pentanedioic Acid is a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor, the enzyme which catabolizes the abundant neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to N-acetylaspartate (NAA) and glutamate. A posiible target in the treatment of multiple sclerosis and Schizophrenia.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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