PhiKan-083 Hydrochloride

Catalogue number: P338500
Chemical name: PhiKan-083 Hydrochloride
Synonyms: 9-Ethyl-N-methyl-9H-carbazole-3-methanamine Hydrochloride;
CAS Number: 880813-36-5
Possible CAS #: NA
Molecular form.: C₁₆H₁₉ClN₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 274.79
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: PhiKan-083 is a p53 stabilizing agent. PhiKan-083 preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan-083 slows rate of thermal denaturation of p53-Y220C.
References: Vousden, K., et al.: Nat. Rev. Cancer., 2, 594 (2002); Olivier, M., et al.: Hum. Mutat., 19, 607 (2002); Ang, H., et al.: J. Biol. Chem., 281, 21934 (2006); Wiman, et al.: Oncogene, 29, 4245 (2010);
Dangerous Goods Info: NA

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  Pack size Price(USD)
10mg $140.00
  Pack size Price(USD)
100mg $1120.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Available in 2-3 weeks

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