6-(2-Phenylethenyl)oxane-2,4-dione

Catalogue number: P319975
Chemical name: 6-(2-Phenylethenyl)oxane-2,4-dione
Synonyms: Dihydro-6-[(1E)-2-phenylethenyl]-2H-pyran-2,4(3H)-dione; 6-[(E)-2-Phenylethenyl]oxane-2,4-dione
CAS Number: 57012-11-0
Possible CAS #: NA
Molecular form.: C₁₃H₁₂O₃
Appearance: Off-White Solid
Melting Point: No Data Available
Mol. Weight: 216.23
Storage: No Data Available
Solubility: Acetone, Dichloromethane, DMSO, Ethyl Acetate, Methanol
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 6-(2-Phenylethenyl)oxane-2,4-dione is an intermediate in the synthesis of rac-Kavain-d3 (K145492), which is the main kavalactone found in the roots of the kava plant. Kavain is known to exhibit anticonvulsive properties by attenuating vascular smooth muscle contraction through interactions with voltage-dependent sodium and calcium channels. rac-Kavain was shown in recent research to exhibit protective properties on anaerobic glycolysis, ATP content and intracellular calcium and sodium of anoxic brain vesicles.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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