(6-{2-[3-(4-Phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl- 4-phenyl-d5-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester

Catalogue number: P319587
Chemical name: (6-{2-[3-(4-Phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl- 4-phenyl-d5-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
Synonyms: (4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenyl-d5-amino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester;
CAS Number: 265989-34-2
Possible CAS #: 125971-95-1 unlabelled
Molecular form.: C₄₀H₄₂D₅FN₂O₅
Appearance: Light-Yellow Foamy Solid
Melting Point: No Data Available
Mol. Weight: 659.84
Storage: No Data Available
Solubility: Acetone, Chloroform, Dichloromethane, Ethyl Acetate
Stability: No Data Available
Category: Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Inhibitors
Boiling Point: No Data Available
Applications: An deuterated intermediate of deuterated Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Dangerous Goods Info: NA
References: Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18. 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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