PHA-793887

Catalogue number: P294480
Chemical name: PHA-793887
Synonyms: 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;
CAS Number: 718630-59-2
Possible CAS #: NA
Molecular form.: C₁₉H₃₁N₅O₂
Appearance: Off-White to Pale Yellow Solid
Melting Point: >147°C (dec.)
Mol. Weight: 361.48
Storage: Hygroscopic, Refrigerator, under inert atmosphere
Solubility: DMSO (Slightly), Methanol(Slightly)
Stability: Hygroscopic
Category: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Boiling Point: No Data Available
Applications: PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
5mg $140.00
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50mg $960.00
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  Pack size Price(USD)
10mg $225.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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