PHA 767491

Catalogue number: P294445
Chemical name: PHA 767491
Synonyms: CAY 10572; 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one
CAS Number: 845714-00-3
Possible CAS #: NA
Molecular form.: C₁₂H₁₁N₃O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 213.24
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators
Boiling Point: No Data Available
Applications: PHA 767491 is a potent and selective ATP-competitive dual inhibitor cdc7/cdk9. It blocks DNA synthesis and affects the phosphorylation of the replicative DNA helicase at Cdc7-dependent phosphorylation sites. Inhibits cell proliferation in a variety of human cell lines and induces apoptosis in a p53-independent manner in vivo. Also inhibits mitogen-activated protein kinase-activated protein kinase-2 (MK-2).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
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10mg $165.00
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50mg $360.00
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5mg $95.00
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25mg $225.00
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250mg $1175.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   Available in 2-3 weeks

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