PF-3644022-d4

Catalogue number: P293827
Chemical name: PF-3644022-d4
Synonyms: (10R)-9,10,11,12-Tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5’,6’:4,5]thieno[3,2-f]quinolin-8-one-d4;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₁H₁₄D₄N₄OS
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 378.48
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Labelled analogue of PF-3644022, a potent freely reversible ATP-competitive compound that inhibits MK2 activity (Ki = 3 nM) with good selectivity when profiled against 200 human kinases. PF-3644022 is a benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor α production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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