PF 06463922

Catalogue number: P293755
Chemical name: PF 06463922
Synonyms: (10R)-7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-Methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile;
CAS Number: 1454846-35-5
Possible CAS #: NA
Molecular form.: C₂₁H₁₉FN₆O₂
Appearance: White Solid
Melting Point: 184-187°C
Mol. Weight: 406.41
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: PF- 06463922 is a potent and selective ROS1/ALK inhibitor capable to block crizotinib-resistant ROS1 mutations. Used in the treatment of human cancers.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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