Catalogue number: P218100
Chemical name: PD-184161
Synonyms: 5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide;
CAS Number: 212631-67-9
Possible CAS #: NA
Molecular form.: C₁₇H₁₃BrClF₂IN₂O₂
Appearance: Off-White Solid
Melting Point: 174-176°C
Mol. Weight: 557.56
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Aromatics, Amines, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators, Pfizer compounds
Boiling Point: No Data Available
Applications: A novel mitogen-activated protein kinase kinase (MEK) inhibitor shown to exhibit antitumor effects and suppress MEK-extracellular signal-related kinase signaling activity and cell proliferation in human hepatocellular carcinoma cells and in human hepatocellular carcinoma xenografts.
Dangerous Goods Info: NA
References: Yip-Schneider, M.T. et al.: J. Pharmacol. Exp. Therap., 329, 1063 (2009); Klein, P.J. et al.: Neoplasia, 8, 1 (2006); Yung, H.W. et al.: Biochem. Pharmacol., 68, 351 (2004);
Peer Review Product Citations:

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10mg $140.00
50mg $565.00
  Pack size Price(USD)
5mg $85.00
25mg $320.00
100mg $995.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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