PD-169316

Catalogue number: P217600
Chemical name: PD-169316
Synonyms: 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine; 4-[5-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-4-yl]pyridine;
CAS Number: 152121-53-4
Possible CAS #: NA
Molecular form.: C₂₀H₁₃FN₄O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 360.34
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Boiling Point: No Data Available
Applications: PD 169316 is a highly selective, potent inhibitor of p38 MAP kinase. PD 169316 inhibits transforming growth factor β-induced Smad signaling in human ovarian cancer cells. PD 169316 acts as an an endogenous suppressor of apoptosis by mimicking CD9, a membrane tetraspanin. Studies show that PD 169316 reduces myocardial ischemia/reperfusion induced voltage-dependent anion channel(VDAC) phosphorylation
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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