Catalogue number: P217490
Chemical name: PD-161570
Synonyms: N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea; 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea;
CAS Number: 192705-80-9
Possible CAS #: NA
Molecular form.: C₂₆H₃₅Cl₂N₇O
Appearance: Off-White Solid
Melting Point: 229-232°C (dec.)
Mol. Weight: 532.51
Storage: Refrigerator
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: Aromatics, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, Pfizer compounds
Boiling Point: No Data Available
Applications: A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells.
Dangerous Goods Info: NA
References: Batley, B.L. et al.: Life Sci., 62, 143 (1997); Hamby, J.M. et al.: J. Med. Chem., 40, 2296 (1997); Nandi, S. et al.: J. Enz. Inhib. Med. Chem., 24, 937 (2009);
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
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