PD-149163

Catalogue number: P217480
Chemical name: PD-149163
Synonyms: N2-[(2S)-2,6-Diaminohexyl]-L-lysyl-L-prolyl-L-tryptophyl-3-methyl-L-valyl-L-leucine Ethyl Ester; PF-01472472; (S)-N-[N-[N-[1-[N2-(2,6-Diaminohexyl)-L-lysyl]-L-prolyl]-L-tryptophyl]-3-methyl-L-valyl]-L-leucine Ethyl Ester;
CAS Number: 169528-11-4
Possible CAS #: NA
Molecular form.: C₄₂H₇₁N₉O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 798.07
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Agonists, Amino Acids & Derivatives, Heterocycles, Inhibitors, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: PD 149163 is a selective, brain penetrating Neurotensin NTR1 receptor agonist. Neurotensin agonists such as PD 149163 block the prepulse inhibition deficits produced by a 5-HT2A and an α1 agonist. As a result, PD 149163 shows pro-cognitive, antipsychotic and anxiolytic effects.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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