PD-123319-d6 Bis(Trifluoroacetic Acid Salt) Salt Hydrate

Catalogue number: P217477
Chemical name: PD-123319-d6 Bis(Trifluoroacetic Acid Salt) Salt Hydrate
Synonyms: (6S)-1-[[4-(Dimethylamino-d6)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid Bis(trifluoroacetate) Salt Hydrate; (S)-(+)-PD 123319-d6 Bis(trifluoroacetate) Salt Hydrate;
CAS Number: 1346603-57-3
Possible CAS #: Unlabelled Freeacid: 130663-39-7; Unlabelled anhyd
Molecular form.: C₃₁H₂₆D₆N₄O₃•2C₂HF₃O₂•xH₂O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 742.69
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: A labelled selective and potent non-peptide angiotensin II type 2 (AT2) receptor antagonist. Potential treatment of cardiac hypertrophy as blockage of AT2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. Studies show that it has protective effect against tumor necrosis factor-α-induced damage to human renal proximal tubular epithelial cells
Dangerous Goods Info: NA
References: Carmeiros-Ramos, M.S. et al.: Bas. Res, Cardiol., 105, 325 (2010); Kagawa, T. et al.: Nephrol., 13, 309 (2008); Cohen, E.P. et al.: Transl. Res., 150, 106 (2007);
Peer Review Product Citations:

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