Catalogue number: P217452
Chemical name: rac-PD-325901-d5
Synonyms: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide-d5; PD 0325901-d5;
CAS Number: NA
Possible CAS #: unlabeled: 391210-10-9
Molecular form.: C₁₆H₉D₅F₃IN₂O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 487.22
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: rac-PD-325901-d5 is the labeled analogue of PD-325901 (P217450). PD-325901 is a mitogenic extracellular kinase 1/2 (MEK1/2) inhibitor and has potent activity in a no. of cancer cell types in vitro.
Dangerous Goods Info: NA
References: Davies, H., et al.: Nature, 417, 949 (2002), Wellbrock, C., et al.: Cancer Res., 64, 2338 (2004), Solit, D., et al.: Cancer Res., 67, 11463 (2007), Adjei, A., et al.: J. Clin. Oncol., 26, 2139 (2008),
Peer Review Product Citations:

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