Catalogue number: P216400
Chemical name: PCI-24781
Synonyms: 3-[(Dimethylamino)methyl]-N-[2-[4-[(hydroxyamino)carbonyl]phenoxy]ethyl]-2-benzofurancarboxamide; CRA 024781; CRA 24781;
CAS Number: 783355-60-2
Possible CAS #: NA
Molecular form.: C₂₁H₂₃N₃O₅
Appearance: White Solid
Melting Point: 200-202ºC (dec.)
Mol. Weight: 397.42
Storage: Refrigerator
Solubility: DMSO, Methanol (Sparingly)
Stability: No Data Available
Category: Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: PCI-24781 is a novel hydroxamic acid HDAC inhibitor (histone deacetylase inhibitor).  PCI-24781 exerts cytotoxicity and histone H3 alterations via caspase-8 and FADD in leukemia cells.
Dangerous Goods Info: NA
References: Morales, V., et al.: Mol. Cell Biol., 20, 7230 (2000), Th’ng, J., et al.: J. Biol. Chem., 280, 27809 (2005), Esteller, M., et al.: Carcinogenesis, 27, 1121 (2006),
Peer Review Product Citations:

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10mg $150.00
  Pack size Price(USD)
100mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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