Panobinostat-d8 (Major) Hydrochloride Salt

Catalogue number: P180502
Chemical name: Panobinostat-d8 (Major) Hydrochloride Salt
Synonyms: (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl-d8)ethyl]amino]methyl]phenyl]-2-propenamide Hydrochloride; LBH 589-d8 Hydrochloride;
CAS Number: NA
Possible CAS #: E/Z Mixture: 1185237-51-7; unlabelled: 404950-80-7
Molecular form.: C₂₁H₁₆D₈ClN₃O₂
Appearance: Tan to Yellow Solid
Melting Point: >150°C (dec.)
Mol. Weight: 393.94
Storage: -20˚C Freezer, Under Inert Atmosphere
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: The novel labelled histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells.
Dangerous Goods Info: NA
References: Claus, R., et al.: Oncogene, 22, 6489 (2003), Johnstone, R., et al.: Cancer Cell., 4, 13 (2003), Ying, J., et al.: Clin. Cancer Res., 11, 6442 (2005), Catley, L., et al.: Blood, 108, 3441 (2006), Steinberg, M., et al.: Clin. Ther., 29, 2289 (2007),
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $140.00
  Pack size Price(USD)
10mg $1120.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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