(S,S)-Palonosetron-d3 Hydrochloride

Catalogue number: P165802
Chemical name: (S,S)-Palonosetron-d3 Hydrochloride
Synonyms: (3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one-d3 Hydrochloride; Aloxi-d3; Onicit-d3; RS-25259-197-d3;
CAS Number: 1246816-81-8
Possible CAS #: 1222442-52-5 free amine, 135729-62-3 unlabelled
Molecular form.: C₁₉H₂₂D₃ClN₂O
Appearance: White to Off-White Solid
Melting Point: >244°C (dec.)
Mol. Weight: 335.89
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
Dangerous Goods Info: NA
References: Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
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