2-Oxo-2-(1-phenyl-1H-pyrazol-4-yl)acetic Acid

Catalogue number: O858630
Chemical name: 2-Oxo-2-(1-phenyl-1H-pyrazol-4-yl)acetic Acid
Synonyms: α-Oxo-1-phenyl-1H-pyrazole-4-acetic Acid
CAS Number: 1152495-65-2
Possible CAS #: NA
Molecular form.: C₁₁H₈N₂O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 216.19
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Miscellaneous Reagents
Boiling Point: No Data Available
Applications: 2-Oxo-2-(1-phenyl-1H-pyrazol-4-yl)acetic Acid is a derivative of N-Phenylpyrazole, a reactant in the synthesis of candesartan cilexetil(C175580), an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.
Dangerous Goods Info: NA
References: Seki, M. et. al: ACS Catalysis, 4, 4047 (2014); Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993; Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)
Peer Review Product Citations:

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