3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester

Catalogue number: O847260
Chemical name: 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester
Synonyms: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-Tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid Methyl Ester; (5α,17β)-3-Oxo-4-azaandrost-1-ene-17-carboxylic Acid Methyl Ester; Methyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate; Finasteride Impurity;
CAS Number: 103335-41-7
Possible CAS #: NA
Molecular form.: C₂₀H₂₉NO₃
Appearance: Off-White Solid
Melting Point: 280-282°C (dec.)
Mol. Weight: 331.45
Storage: Refrigerator
Solubility: Chloroform, DMSO, Methanol
Stability: No Data Available
Category: Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Boiling Point: No Data Available
Applications: Finasteride (F342000) and Dutasteride (D735000) impurity. An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. Finasteride impurity.
Dangerous Goods Info: NA
References: Bakshi., et al.: J. Med. Chem., 38, 3189 (1995),
Peer Review Product Citations:

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