3-Oxo Atorvastatin tert-Butyl Ester

Catalogue number: O847145
Chemical name: 3-Oxo Atorvastatin tert-Butyl Ester
Synonyms: (δR)-2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)-β-oxo-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester; (R)-2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)-β-oxo-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester
CAS Number: 134394-98-2
Possible CAS #: NA
Molecular form.: C₃₇H₄₁FN₂O₅
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 612.73
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Chiral Reagents, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 3-Oxo Atorvastatin tert-Butyl Ester is a Boc-protected oxo-derivative of Atorvastatin (A791750, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin can also lower both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
Dangerous Goods Info: NA
References: Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)
Peer Review Product Citations:

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