Catalogue number: O712500
Chemical name: Otamixaban
Synonyms: (αR)-3-(Aminoiminomethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]benzenepropanoic Acid Methyl Ester; [R-(R*,R*)]-3-(Aminoiminomethyl)-α-[1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]benzenepropanoic Acid Methyl Ester; FXV 673; Methyl (2R,3R)-2-[3-Amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate;
CAS Number: 193153-04-7
Possible CAS #: NA
Molecular form.: C₂₅H₂₆N₄O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 446.5
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: A potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. Clinical studies show that it is efficacious, safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome.
Dangerous Goods Info: NA
References: Guertin, K.R. et al.: Curr. Med. Chem., 14, 2471 (2007); Hinder, M. et al.: Clin. Pharmacol. Therap., 80, 691 (2006); Hinder, M. et al.: Thromb. Haemost., 95, 224 (2006);
Peer Review Product Citations:

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