Octyl-α-hydroxyglutarate

Catalogue number: O287590
Chemical name: Octyl-α-hydroxyglutarate
Synonyms: Octyl-2-HG;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₁₃H₂₄O₅
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 260.33
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Octyl-α-hydroxyglutarate is a cell-permeable derivative of 2-HG (α-hydroxyglutaric acid). Mutations in isocitrate dehydrogenase 1 (IDH1 and IDH2) associated with certain cancers cause isocitrate to metabolize into 2-HG as opposed α-ketoglutarate, inhibiting α-ketoglutarate-dependant dioxygenases including lysine demethylases and DNA hydroxylases.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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